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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Rare and Unusual Occurrence of a Malignant Rhabdoid Tumor in a Pediatric Dual Kidney Transplant Recipient‐Challenges in Diagnosis and Management

Nagendra Parvataneni, Amulya Chiliki, Diwakar Naidu, Isatish Rao, P. Susmitha, Ishfaq Ahmed, Mahesh Chejarla, G. Reshma Sree and Indrani Biswas
Page: 579-582 | Received 18 Oct 2024, Published online: 13 Dec 2024

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https://doi.org/10.36478/10.36478/makrjms.2025.1.579.582

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Abstract

Renal transplantation is a critical treatment for end‐stage renal disease, and pediatric cadaveric dual kidney en bloc transplants provide a valuable option for renal replacement. This case report discusses the rare incidence of a Malignant Rhabdoid Tumor (MRT) in a dual kidney transplant recipient, emphasizing the challenges in diagnosis and management. A 57‐year‐old female, with a history of hypertension and chronic kidney disease, received a pediatric cadaveric dual kidney en bloc transplant. Eleven months post‐transplant, she developed severe abdominal pain. Imaging suggested a hypodense lesion in the transplanted kidney. Differential diagnosis considered post‐transplant lymphoproliferative disorder and Wilms tumor. Following a graft nephrectomy due to complications, histopathology confirmed an MRT. Management included extensive surgery, immunosuppressive adjustment and adjuvant therapy. Immunol is to chemistry indicated loss of INI‐1 expression in the tumor, crucial for the diagnosis. MRT in transplanted kidneys is an unusual but serious complication post‐transplant. This case underscores the necessity for vigilant follow‐up, comprehensive diagnostic strategies and individualized treatment plans to manage such rare occurrences effectively.

How to cite this article:

Nagendra Parvataneni, Amulya Chiliki, Diwakar Naidu, Isatish Rao, P. Susmitha, Ishfaq Ahmed, Mahesh Chejarla, G. Reshma Sree and Indrani Biswas. A Rare and Unusual Occurrence of a Malignant Rhabdoid Tumor in a Pediatric Dual Kidney Transplant Recipient‐Challenges in Diagnosis and Management.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.579.582
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.579.582