Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Palmoplantar psoriasis (PPP) and palmoplantar eczema (PPE) are chronic dermatological conditions with overlapping clinical and histopathological features, making accurate diagnosis challenging. Dermoscopy is increasingly being used as a non‐invasive tool to distinguish between these conditions. To compare the dermoscopic and histopathological findings of PPP and PPE and assess the correlation between clinical, dermoscopic and histopathological observations. This hospital‐based, prospective, observational study included 54 patients (32 PPP and 22 PPE) aged 31‐70 years. Clinical examination, dermoscopy using a 4th generation DermLite (DL4) and histopathological analysis were performed. Statistical analysis was conducted using SPSS version 25, with p<0.05 considered significant. The mean disease duration was 1.84±0.46 years for PPP and 2.21±0.64 years for PPE. Dermoscopic findings showed significant differences: dot vessels were more common in PPP (59%, p=0.0209), while yellow scales (54.5%, p<0.0001) and patchy scale distribution (86.3%, p<0.0001) were characteristic of PPE. Histopathologically, parakeratosis (78%), hypogranulosis (37.5%) and peri vascular infiltrates (60%) were predominant in PPP, whereas PPE demonstrated higher spongiosis (77%) and mixed inflammatory infiltration. Dermoscopic correlation was noted in 50% of PPP and 59% of PPE cases, with limitations in darker skin types and keratoderma. Dermoscopy, complemented by histopathology, is a valuable diagnostic tool for differentiating PPP and PPE. This study highlights specific dermoscopic and histopathological features that aid in accurate diagnosis and management.
How to cite this article:
Sameera Boda, Metta Arun Kumar and Turpati Narayana Rao. Dermoscopic and Histopathological Comparison of Palmoplantar Psoriasis and Eczema: A Clinico‐Pathological Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.428.432
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.428.432