files/journal/2022-09-03_18-51-40-000000_599.png

Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
About US
Editors
Issues
Pages
Indexed in
110
Views
4
Downloads

Comparative Study of the Efficacy of Intravenous Paracetamol and Intramuscular Paracetamol in Combination with Intravenous Tramadol for Post‐ Operative Analgesia in Open Appendectomy Patients

Amala Devasia, Vyankatesh S. Joshi, Kiran Todkari and Vaibhavi Vijay Sakhale
Page: 374-378 | Received 01 Nov 2024, Published online: 27 Dec 2024

Download Citation
https://doi.org/10.36478/10.36478/makrjms.2025.1.374.378

Full Text Reference XML File PDF File

Abstract

Non‐steroidal anti‐inflammatory drugs and opioids are routinely used to mitigate post‐operative pain., however these drugs are burdened by side effects. Tramadol and paracetamol are believed to be lacking in such side effects. To compare the efficacy of intravenous Paracetamol with intramuscular paracetamol in combination with intravenous tramadol for post‐operative analgesia in open appendectomy patients. This was a randomized controlled double‐blinded study. A total of 120 patients were selected and randomized into two groups of sixty patients each, Group A (Inj paracetamol 15mg/kg IM+Inj tramadol 50mg IV) and Group B (Inj paracetamol 1gm IV infusion+Inj tramadol 50mg IV was used) undergoing open appendectomy elective or emergency surgery under spinal anesthesia. Duration of analgesia after surgery, visual analog scale score and hemodynamic parameters were recorded. Statistical software SPSS 24.0 version IBM USA was used for data analysis. We observed that the mean duration of analgesia was better in Group A as compared to Group B which was statistically significant (p<0.05). The VAS score was significantly less in Group A as compared to Group B at 5 and 6 hours after surgery. Post‐operative complications were negligible in both the groups. Mean duration of analgesia was less in intravenous paracetamol group as compared to intramuscular group.

How to cite this article:

Amala Devasia, Vyankatesh S. Joshi, Kiran Todkari and Vaibhavi Vijay Sakhale. Comparative Study of the Efficacy of Intravenous Paracetamol and Intramuscular Paracetamol in Combination with Intravenous Tramadol for Post‐ Operative Analgesia in Open Appendectomy Patients.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.374.378
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.374.378