Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
The Severe Acute Respiratory Syndrome virus (SARS‐CoV‐2) that causes corona virus disease 2019 (COVID‐19) was discovered in Wuhan, Hubei, China in December 2019, leading to a number of pneumonia cases. An epidemic was caused by the disease's quick spread and novelty combined with a lack of targeted action. The aims to determine the correlation of COVID‐19 patients by systematically analyzing the baseline biochemical characteristic and laboratory indices. This is a hospital based; observational cross‐sectional study was conducted in department of pathology medical college Kolkata in collaboration with department of chest medicine. The study period was One year. 382 patients were included in this study. In Mild, the mean LDH (mean±s.d.) of patients was 248.7961±79.7309. In Moderate, the mean LDH (mean±s.d.) of patients was 301.1972±93.0326. In Severe, the mean LDH (mean±s.d.) of patients was 463.5287±207.2682. Distribution of mean LDH with Severity was statistically significant (p<0.0001). In Mild, the mean Ferritin (mean±s.d.) of patients was 299.4790±225.5873. In Moderate, the mean Ferritin (mean±s.d.) of patients was 913.6915± 1365.3716. In Severe, the mean Ferritin (mean±s.d.) of patients was 1883.4747±2348.1545. Distribution of mean Ferritin with Severity was statistically significant (p<0.0001). In summary, the relationship between the severity of the disease and biochemical traits in COVID‐19 patients provides important information on the pathogenesis of the virus. Higher levels of several biomarkers‐like ferritin, D‐dimer, C‐reactive protein and liver enzymes‐are closely linked to worsening illness outcomes. These biochemical measures can be useful markers for identifying high‐risk individuals early on, which can help with prompt management and intervention plans.
How to cite this article:
Sneha Barman, Sumit Ray and Rashmi Singh. Correlation of Disease Severity with Biochemical Characteristic of Patients with COVID‐19: A Single Centre Tertiary Care Covid Hospital Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.319.323
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.319.323