Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
The Polycystic Ovarian Syndrome (PCOS) is a prevalent endocrine disorder among women of reproductive age, characterized by hyperandrogenism, chronic an ovulation and polycystic ovaries. The syndrome presents with diverse menstrual irregularities, influenced by hormonal imbalances such as hyperestrogenism. To examine the correlation between endometrial thickness and astraddle levels with the clinical presentation of menstrual patterns in women diagnosed with PCOS. A cross‐sectional observational study involving 100 patients diagnosed with PCOS per the Rotterdam criteria was conducted from May to October 2024 at RNT Medical College, Udaipur. The study assessed the endometrial status and serum astraddle levels in relation to menstrual patterns among participants. The study revealed that 97% of participants presented with menstrual complaints. Hyper estrogenic states were associated with varied menstrual patterns, notably oligomenorrhoea, which was the most common presentation. Notably, 15% of patients with oligomenorrhoea had menorrhagia with a corresponding increase in endometrial thickness. Despite elevated astraddle levels, a significant proportion of participants had normal endometrial thickness, indicating a disconnect between estrogen levels and endometrial response. The findings suggest that while hyperestrogenism impacts the frequency and volume of menstrual bleeding, it does not uniformly affect endometrial thickness in women with PCOS. This highlights the complexity of hormonal interactions in PCOS and suggests potential areas for further study, including the inclusion of estrogen levels as a diagnostic criterion for PCOS.
How to cite this article:
Meenal Chugh, Bharat Bilwal, Chanchal Arora and Vismandeep Kaur Sandhu. Association of Endometrial Status and Estrogen Levels with Varying Menstrual Patterns in PCOS.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.287.291
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.287.291