Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Postpartum anemia (PPA) is a common condition that affects maternal recovery and overall health, particularly in developing countries. Intravenous (IV) iron formulations, such as ferric carboxymaltose (FCM) and iron sucrose (IS), are effective for rapid correction of iron deficiency, but their safety profiles require further evaluation. The study aimed to evaluate and compare the safety of ferric carboxymaltose and iron sucrose in postpartum anemia by analyzing adverse effects and complications in postpartum women. This was a prospective, comparative study conducted on postpartum women diagnosed with moderate ‐to‐severe anemia. Participants were divided into two groups: Group A received ferric carboxymaltose and Group B received iron sucrose. Adverse reactions and complications such as headache, nausea, myalgia and other side effects were recorded and compared between the groups. Statistical analysis was performed using the Chi‐square test, with a p‐value <0.05 considered significant. A total of 100 women participated, with 50 in each group. Group A (FCM) reported minor complications, including headache (2%), myalgia (4%) and nausea (1%), whereas Group B (IS) showed no adverse effects (p>0.05). Most participants in Group A (92%) and Group B (100%) experienced no complications. Both ferric carboxymaltose and iron sucrose demonstrated excellent safety profiles in postpartum women with anemia. While FCM caused minor adverse reactions, these were transient and resolved without intervention. Iron sucrose remained free of adverse effects, indicating both are safe options for clinical use.
How to cite this article:
Geddam Swarupa, M.V. Anusha Rani and Aruna Yarasani. Evaluation of Safety of Ferric Carboxymaltose and Iron Sucrose in Postpartum Anaemia.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.233.236
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.233.236