Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Primary Cutaneous CD8+Aggressive Epidermotropic Cytotoxic T‐Cell Lymphoma (PCAE‐CTL) is a rare and aggressive variant of cutaneous T‐cell lymphoma. We present a case of a 29‐year‐old male with an unusual presentation of PCAE‐CTL, characterized by crusted, fungating skin lesions, significant weight loss and a mild fever. The patient exhibited striking clinical features, including extensive skin lesions over the body. Biopsy findings revealed an epidermotropic infiltration of large lymphocytes with papillary dermal edema. Immunohistochemistry confirmed a CD8+T‐cell lineage. PET‐CT demonstrated multiple hyper metabolic subcutaneous nodules and ultrasound revealed hepatomegaly, splenomegaly and enlarged mesenteric lymph nodes. Initial antibiotic therapy with piperacillin‐tazobactam yielded no improvement, leading to a shift to meropenem and clarithromycin. Unfortunately, the patient's health deteriorated rapidly and he passed away before chemotherapy initiation.
How to cite this article:
Rais Ahemad A.Patvegar and Vaibhav V. Bisne. Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T‐Cell Lymphoma: A Case Report.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.2.419.422
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.2.419.422