Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Dexmedetomidine and Clonidine opiates that are alpha‐2 adrenergic agonists have been identified to be potential agents in producing targeted hypotension in FESS. These agents have related actions that mostly work in the central nervous system by suppressing sympathetic activity which results to hypotension and bradycardia. The main objective of the study is to find the comparison of dexmedetomidine, with clonidine based anaesthesiafor controlled hypotension in functional endoscopic sinus surgery. This randomized, controlled trial was conducted at wamy vivekananda medical College and hospital, tiruchengode, Tamilnadu. A total of 80 patients scheduled for elective FESS were enrolled in the study. All patients were premedicated with oral diazepam 5 mg the night before surgery. Once in the operating room the usual preoperative baseline was recorded and connected to the ECG, NIBP, pulse oximeter and capnograph. Data were collected from 80 patients. The average age was similar, with Group D (Dexmedetomidine) at 45.36±10.01 years and Group C (Clonidine) at 44.45±9.91 years. Gender distribution was also comparable, with Group D having 22 males and 18 females, while Group C had 24 males and 16 females. The mean BMI was nearly identical between the groups, with Group D at 25.6±3.2 kg/m² and Group C at 25.8±3.1 kg/m². It is concluded that Dexmedetomidine is more effective than Clonidine in achieving controlled hypotension during Functional Endoscopic Sinus Surgery, offering better surgical field conditions, reduced intraoperative blood loss and a smoother postoperative recovery.
How to cite this article:
D.V. Praveen, K. Jayasudha and S. Ramesh Kumar. Comparison of Dexmedetomidine, with Clonidine Based Anaesthesia for Controlled Hypotension in Functional Endoscopic Sinus Surgery.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.91.96
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.91.96