Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Autism spectrum disorder (ASD) is a complex and mysterious neurodevelopmental disorder that appears in the early years of life. Autistic children are characterized by impaired social interaction and communication and fail to respond to certain stimuli exhibiting some restricted and repetitive behavior or action. To evaluate vitamin status [Vit. D and Vit.B12] in children with autism spectrum disorder and Its correlation with severity of Disease. This comparative study includes75 autism spectrum disorder patients of age. Group 2‐15 years as well as age, gender, matched 25 healthy children as controls. The degree of ASD Severity was diagnosed by clinical psychologist by using Indian scale for assessment of autism (ISAA Score). Blood samples were collected from all participants and analyzed for vitamin D, vitamin B12. The Obtained Results were analyzed statistically to calculate significance of difference among them by calculating p value. Significantly decrease levels of serum vitamin D and vitamin B12 were found in ASD patients as compared to healthy controls and Vit D and Vit. B12 deficiency were found to be strongly correlated with ASD severity. Vit D and Vit B12 deficiencies are prevalent in children with ASD and Deficiency of Vit D and B12 correlate with disease severity. Early detection and targeted supplementation may serve as adjunctive strategies in ASD management.
How to cite this article:
Vijay Laxmi Nangliya, Renu Meena, Shyam Sunder, Lucky Ahuja and Narayan Yadav. A Study of Vitamins D and B12 Levels in Autism Spectrum Disorder Children and their Relation with Disease Severity.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.568.571
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.568.571