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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Assessing the Impact of Lifestyle Interventions on Nonalcoholic Fatty Liver Disease Progression: A Prospective Cohort Study

J. Gayathri and K.P. Selvarajan Chettiar
Page: 545-550 | Received 20 Sep 2024, Published online: 08 Oct 2024

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Abstract

In Asian adults, the prevalence of nonalcoholic fatty liver disease (NAFLD) can approach 30%., patients who are obese have a higher prevalence of NAFLD. Although difficult to accomplish, weight loss is usually advised for individuals with NAFLD or those at high risk. Our goal was to assess how a mobile app‐based lifestyle intervention affected NAFLD patients' ability to lose weight. All participants were provided with a standardized model digital weighing scale (Omron HN‐286, Japan) for self‐monitoring of weight. All outcomes were part of routine measurements taken by trained nurses and blood tests conducted at the outpatient NAFLD clinic. Assessors were not blinded to the groups allocated to the study participants. Body weight was measured using a calibrated digital weighing machine (Seca 767, Germany) to the nearest 0.1 kg. Height was measured in meters to two decimal points using the stadiometer attached to the Seca scale and the corresponding BMI was calculated. There were a significantly greater number of participants who achieved ~5% weight loss in the intervention as compared to the control group at both 3 and 6 months (Table 2). After adjustment for age, gender and ethnicity, the intention‐to‐treat and per‐protocol analyses showed that use of the mobile‐enabled lifestyle intervention program was independently associated with a higher likelihood of achieving a ~5% weight loss at 3 and 6 months when compared with standard care. Patients with NAFLD may benefit from a lifestyle intervention that is made possible by a mobile app, since it can improve their liver enzyme levels and anthropometric indices. There is a chance that this therapeutic approach will be used on a broader demographic.


How to cite this article:

J. Gayathri and K.P. Selvarajan Chettiar. Assessing the Impact of Lifestyle Interventions on Nonalcoholic Fatty Liver Disease Progression: A Prospective Cohort Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.545.550
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.545.550