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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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To Study the Serum Ferritin Level in Chronic Liver Disease and it’s Correlation with Child Turcotte Pugh Score

P. Abhay Kiran, Arjun Krishnakumar, Shivanaik Rayanaikar, Akshath A. Hegde and Ishwara C. Havaragi
Page: 188-192 | Received 30 Jul 2024, Published online: 12 Sep 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.10.188.192

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Abstract

Liver cirrhosis has been established as the condition where normal liver parenchyma is replaced with connective tissue producing nodule formation. Child‐Pugh score has been used to assess the severity of liver dysfunction in clinical work. Serum ferritin is universally available biochemical parameter and is elevated in several clinical conditions including patients with chronic liver disease. To estimate the serum ferritin level in liver Cirrhosis and to assess any significant correlation between ferritin level and CTP score. The present study was carried out in the Department of General Medicine, KIMS, Hubballi. Patients who were clinically diagnosed with CLD and were eligible for the study according to the above‐mentioned eligibility criteria were included in the study after informed consent from the patient. All necessary investigations were performed and the severity of CLD was defined as per CTP Criteria. In the study, the mean age of the subjects was 45.16 years. The most common grade of hepatic encephalopathy was Grade 2 (16.7%). The mean CTP Score among the subjects was 10.2 Majority belonged to Class c (49.1%). The mean MELD score among the subjects was 22.90. The mean serum ferritin score among the subjects was 364. The mortality rate in the study was 10.5%. There is a significant and positive correlation between serum ferritin levels and CTP score is evident among liver cirrhosis patients. In this study, CTP classification which was done to access severity and prognosis of cirrhosis also showed higher ferritin levels with increasing class. Hence, as the severity of the liver disease increases, it is associated with increased in serum ferritin levels. These findings point toward a possible prognostic value of serum ferritin in CLD.

How to cite this article:

P. Abhay Kiran, Arjun Krishnakumar, Shivanaik Rayanaikar, Akshath A. Hegde and Ishwara C. Havaragi. To Study the Serum Ferritin Level in Chronic Liver Disease and it’s Correlation with Child Turcotte Pugh Score.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.188.192
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.188.192