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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Study of Comparison of SPO2/FIO2 Ratio with PAO2/FIO2 Ratio in Patients with Acute Respiratory Distress Syndrome and Acute Lung Injury

Arjun Krishnakumar, Shivanaik Rayanaikar, Ishwara C. Havaragi, Akshath A. Hegde and Niranjan Gangoor
Page: 170-175 | Received 30 Jul 2024, Published online: 12 Sep 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.10.170.175

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Abstract

ALI and ARDS are two of the most severe respiratory syndromes. In line with the AECC in 1994, PaO2/FiO2 ratios of <300 and <200 are used to define ARDS and ALI respectively. ABG is an invasive investigation used to obtain PaO2 values from arterial blood. ABG is not easily available in resource poor settings. SpO2 is a non‐invasive measurement of blood oxygen content. SpO2/FiO2 ratio has been proposed as a surrogate for PaO2/FiO2 for diagnosis of ARDS and ALI. This study was undertaken to assess correlation between SpO2/FiO2 and PaO2/FiO2 in critically ill patients with ALI and ARDS and to determine the efficacy of SpO2/FiO2 in diagnosing ALI or ARDS. To study the correlation between SpO2/FiO2 and PaO2/FiO2 in critically ill patients with ALI and ARDS and to determine the efficacy of SpO2/FiO2 ratio compared to PaO2/FiO2 ratio in diagnosing ALI and ARDS in critically ill patients.150 patients diagnosed as ARDS and ALI were included in the study after applying inclusion, exclusion criteria. History, clinical examination and relevant investigations were done. Data was entered in excel sheet and statistical analysis done using SPSS software. In critically ill patients who are getting admitted in MICU of KIMS hospital, SpO2/FiO2 and PaO2/FiO2 ratios have good positive correlation (r‐0.995, p<0.001) and SpO2/FiO2 can be used for the diagnosis of ALI (sensitivity and specificity of 100%) and ARDS (sensitivity of 100%, specificity of 97.6%). SpO2/FiO2 can be used as a surrogate for PaO2/FiO2 ratio for the diagnosis of ARDS and ALI with high sensitivity and specificity in critically ill patients who are getting admitted in MICU of KIMS hospital. However, this was a monocentric study with a study population of 150. More studies are needed for a definitive conclusion.

How to cite this article:

Arjun Krishnakumar, Shivanaik Rayanaikar, Ishwara C. Havaragi, Akshath A. Hegde and Niranjan Gangoor. A Study of Comparison of SPO2/FIO2 Ratio with PAO2/FIO2 Ratio in Patients with Acute Respiratory Distress Syndrome and Acute Lung Injury.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.10.170.175
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.10.170.175