Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Our goal was to investigate the correlation between preoperative carcinoembryonic antigen (CEA) levels and TNM (tumour, node, distant metastatic, or metastasis) staging in patients with colorectal cancer in our locality. For the purpose of staging colorectal cancer, the American Joint Committee on Cancer/Union for International Cancer Control used the TNM classification system, which stands for primary tumour, lymph node and metastasis (M). This method was used to classify patients with colorectal cancer into four categories: Stage I (tumour without lymph node involvement up to subserosa), Stage II (tumour without lymph node involvement beyond subserosa), Stage III (tumour without lymph node involvement without metastasis) and Stage IV (metastatic tumour). Data from 772 individuals who received a colorectal cancer diagnosis between 1992 and 2010 were assessed in this research. Out of the 772 patients, 335 (43.2%) and 437 (56.8%) were female. With a median age of 57 years, the mean age was 57.7±15.8 years. There was no statistically significant correlation seen between the CEA levels and tumour diameter, TNM staging, or tumour differentiation level, even though the CEA levels of 52.2% of the patients that were included were within normal ranges. The study suggests that most people with colorectal cancer may have CEA levels within normal ranges. Consequently, a colon cancer diagnosis cannot be ruled out by normal CEA values and it may be inferred that these individuals need further investigation.
How to cite this article:
Gowbath Marliya, Parameswaran Unnithan and Pallamala Lasya. Assessment of the Association Between Carcinoembryonic Antigen and TNM Stage in Colorectal Cancer.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.1.395.398
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.1.395.398