Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
To evaluate the maternal and perinatal outcomes in pregnancies complicated by thyroid dysfunction and identify associated risk factors. A prospective cohort study was conducted on 200 pregnant women with thyroid dysfunction, including 186 (93%) with hypothyroidism and 14 (7%) with hyperthyroidism. Maternal and fetal outcomes were compared between the two groups using chi‐square tests and logistic regression analysis. The prevalence of preeclampsia was significantly higher in the hyperthyroidism group (35.7%) compared to the hypothyroidism group (15.1%) (p=0.04). Neonatal respiratory distress was also more prevalent in the hyperthyroidism group (28.6%) than in the hypothyroidism group (10.8%) (p=0.05). After adjusting for confounders, hyperthyroidism was significantly associated with an increased risk of preeclampsia (aOR: 3.12, 95% CI: 1.01‐9.69, p=0.049) compared to hypothyroidism. The prevalence of anemia in pregnancy, preeclampsia, preterm birth, low birth weight, and neonatal respiratory distress increased significantly with the severity of hypothyroidism (p<0.05). Thyroid disorders, particularly hyper thyroids, are associated with adverse maternal and fetal outcomes in pregnancy. The increased risk of preeclampsia in women with hyperthyroidism and the higher prevalence of adverse outcomes with increasing severity of hypothyroidism highlight the importance of early diagnosis and appropriate management of thyroid dysfunction in pregnancy.
How to cite this article:
Aditya Vikram, Priya Sharma and Aditi Vikram. Impact of Thyroid Disorders on Maternal and Fetal Outcomes in Pregnancy.
DOI: https://doi.org/10.36478/10.36478/makrjms.2022.108.115
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2022.108.115