Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Random blood sugar level is one of the factors which influence the severity of the Organophosphorus compound poisoning. This study aims to predict the prognosis and mortality of Organophosphorus compound poisoning based on random blood sugar level and correlate it with pseudocholinesterase activity. 103 cases of OP poisoning were studied. Patients above 18 years of age were included and those patients with mixed poisoning, alcohol consumption and Diabetes were excluded. Detailed history and clinical examination was done according to the proforma with special reference to the need for ventilatory support, admission RBS and pseudocholinesterase levels. Of the 103 patients, males were 57%, females 43%, majority were between 18‐25 years with farmers (55%) as the main group and suicidal ingestion (90%) as the main cause. Methyl parathion was the commonest compound (15%) consumed but most of the time the compound was unknown (33%). Commonest symptoms were vomiting (94%) and salivation (94%). Respiratory failure was the commonest complication (30%). Hyperglycemia occurred in 39% of patients with 73% developing complications and 50% requiring ventilator. Pseudocholinesterase was <4000U/L in 19% of patients, with complications occurring in 100% and 79% requiring ventilator support. Mortality was 35% in patients with hyperglycemia (p<0.05S) and 79% in patients with pseudo cholinesterase <4000U/L (p<0.001 HS). Admission Random Blood sugar >200mg/dl and Pseudo cholinesterase <4000 U/L are reliable parameters to predict mortality and ventilator requirement in organo phosphorous compound poisoning. By Chi Square Test, drop in Pseudocholinesterase level and increase in blood sugar level were associated with ventilator requirements, mortality and complications and was found to be significant.
How to cite this article:
James Milton Aifred and Seethepalli Venkata Ramana. A Prospective Study of Blood Sugar as a Prognostic Indicator in Organophosphorus Compound Poisoning.
DOI: https://doi.org/10.36478/10.36478/makrjms.2017.6.224.228
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2017.6.224.228