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Journal of Animal and Veterinary Advances

ISSN: Online 1993-601X
ISSN: Print 1680-5593
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Effects of Grape Seed Extract on Renal Ischemic Reperfusion in Rats

Seyed Ashrafadin Goushegir, Yousef Doustar, Fataneh Hashem Dabaghian and Mehrdad Hashemi
Page: 2529-2532 | Received 21 Sep 2022, Published online: 21 Sep 2022

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Abstract

Grape Seed Extract (GSE) has been reported to exert protective effects on various forms of renal ischemic reperfusion disorders. Natural Grape Seed Extract (GSE) are potent free radical scavengers and hence, provide significant protection against oxidative stress. Accordingly, the present study focused on investigating the possible protective role of GSE against ischemic reperfusion mediated damage in renal tissues in rats. The results revealed that oral administration of 250 mg kg-1 (body weight) of GSE for 3 days significantly protect against renal cell apoptosis via the induction of endogenous antioxidant (p<0.001).


How to cite this article:

Seyed Ashrafadin Goushegir, Yousef Doustar, Fataneh Hashem Dabaghian and Mehrdad Hashemi. Effects of Grape Seed Extract on Renal Ischemic Reperfusion in Rats.
DOI: https://doi.org/10.36478/javaa.2012.2529.2532
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2012.2529.2532