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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Study on Efficacy of Injectable Platelet Rich Fibrin for Androgenetic Alopecia in Males

D.V. Praveen Kumar Raju, Bogula Sivaji Yadav, Ramala Amala, T. Nirupama Bhagyalakshmi and K. Hari Krishna
Page: 531-534 | Received 20 Oct 2024, Published online: 30 Dec 2024

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https://doi.org/10.36478/10.36478/makrjms.2025.1.531.534

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Abstract

Androgenetic alopecia (AGA) is the most common cause of hair loss, affecting men and women worldwide, with characteristic patterns like a receding hairline or diffuse thinning. It results from a shortened hair growth cycle, producing thinner, shorter hairs. Androgenetic Alopecia can affect all races, but the prevalence rates vary. Prevalence is highest in Caucasians. As the anagen phase determines the hair length, the maximum length of the new anagen hair becomes shorter than that of its predecessor, leading to miniaturization and eventually a bald appearance. Conventional FDA Approved treatments for male AGA include topic/oral Minoxidil and oral Finasteride. Additional procedural therapies like Platelet‐Rich Plasma (PRP) and hair transplantation are available for both genders. Injectable Platelet‐Rich Fibrin (I‐PRF), a second‐generation bio material, provides sustained release of growth factors due to its fibrin network, enhancing therapeutic effects and reducing treatment sessions. To demonstrate the efficacy of I‐PRF in the enhancement of hair growth among the male patients with Androgenetic alopecia and to measure the outcomes through follow up every month till 5 months. A prospective interventional study in which 20 patients with AGA were assessed clinically using Hamilton grading and by trichoscope. I‐PRF is done monthly once and outcomes were assessed every month till week 20 using investigator assessment scale and patient scale. We identified 20 patients with AGA with duration of disease 3 year. At the end of 20 weeks of treatment, the hair count on USB microscope lens in one cm diameter was significantly high using this i‐PRF treatment. The mean observer scale (2.70±0.47 vs 1.9±0.71., p=0.0002) and patient scale (3.5±0.60 vs 2.75±0.78., p=0.0016) was significantly high. I‐PRF treatment once 4 weekly as a single modality of treatment in patients with AGA was very effective in the enhancement of hair growth among the male patients with AGA.

How to cite this article:

D.V. Praveen Kumar Raju, Bogula Sivaji Yadav, Ramala Amala, T. Nirupama Bhagyalakshmi and K. Hari Krishna. A Study on Efficacy of Injectable Platelet Rich Fibrin for Androgenetic Alopecia in Males.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.531.534
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.531.534