TY  - JOUR
T1  - Study the Secondary Pathological Lesions
AU - H. Al-Jeboori, Khalil AU - R. Suhail, Sattar 
JO  - Veterinary Research
VL  - 11
IS  - 2
SP  - 14
EP  - 19
PY  - 2018
DA  - 2001/08/19
SN  - 1993-5412
DO  - vr.2018.14.19
UR  - https://makhillpublications.co/view-article.php?doi=vr.2018.14.19
KW  - LPS
KW  -pathological findings
KW  -Immunization
KW  -OMP
KW  -granulomatous lesion
AB  - Snuffles disease is a major infectious disease
process in rabbits caused by Pasteurella multocida. The
importance of the Lipopolysaccharides (LPS) and Outer
Membrane Protein (OMP) in the immunization and
pathogenesis of the disease. This study aimed to identify
all the pathological findings in rabbits immunized with
LPS and OMP. For this reason a local strain of
Pasteurella multocida were used and their LPS and OMP
were extracted and purified and used for immunization of
rabbits. Following immunization and inoculation of a
challenge dose of the Pasteurella multocida, the bacterial
Isolation were mild to moderate at 4th, 8th day and mild
at 16th day post inoculation compared to heavy bacterial
isolates in the control non immunized group. Also, more
localized and granulomatous lesion were seen in
immunized groups compared to extensive and diffuse
septicemic lesions in non immunized control group.
ER  -