TY  - JOUR
T1  - Assessment of Dietary Bovine Lactoferrin in Enhancement of Immune Function and Disease Resistance in Common Carp (<I>Cyprinus carpio</I>)
AU - Lashkarbolooki, Mohammad AU - Iranshahi, Farnaz AU - Kiaalvandi, Saeed AU - Faramarzi, Moein 
JO  - Journal of Fisheries International
VL  - 6
IS  - 2
SP  - 41
EP  - 45
PY  - 2011
DA  - 2001/08/19
SN  - 1817-3381
DO  - jfish.2011.41.45
UR  - https://makhillpublications.co/view-article.php?doi=jfish.2011.41.45
KW  - Cyprinus carpio
KW  -A. hydrophilla
KW  -Lctoferrin
KW  -lymphocytes
KW  -supplementention
KW  -Iran
AB  - Lctoferrin (LF) is an iron-binding glycoprotein plays an important role in the non-specific immune system in fish and mammals. Common carp (<I>Cyprinus carpio</I>) was fed bovine LF supplemented diets (0, 200, 400 and 600 mg kg<SUP>-1</SUP> diet) for 4 weeks. The effect of dietary LF on immune function and resistance to <I>Aeromonas hydrophilla</I> challenge was determined. The level of LF in diet had a significant force on survival following <I> A. hydrophilla</I> challenge with fish fed the 600 mg kg<SUP>-1</SUP> LF diet having significantly superior survival than control fish. There was increase in activity of non-specific and specific immune parameters (lymphocytes count, macrophage oxidative burst, serum lysozyme and bactericidal activities against <I>A. hydrophilla</I>) with addition of LF to diets. While there was not a corresponding increase in activity of total leukocytic count and neutrophil adhesion test. The increased resistance to <I>A. hydrophilla</I> with increasing dietary concentration of LF seemed to correspond with an enhancement of non-specific immune functions. In conclusion, dietary LF supplementation could be enhances the non-specific immunity and diseases resistance in common carp (<I>Cyprinus carpio</I>).
ER  -