TY  - JOUR
T1  - Multiphysics Modeling for Bone Remodeling Simulation: A Methodological Framework
AU - Balaguera, Manuel Ignacio AU - Acuna, Robayo AU - Vivana, Paula AU - Viloria, Amelec AU - Gaitan, Mercedes AU - Lis, Jenny Paola 
JO  - Journal of Engineering and Applied Sciences
VL  - 12
IS  - 11
SP  - 2889
EP  - 2896
PY  - 2017
DA  - 2001/08/19
SN  - 1816-949x
DO  - jeasci.2017.2889.2896
UR  - https://makhillpublications.co/view-article.php?doi=jeasci.2017.2889.2896
KW  - multiphysics modeling
KW  - multiphysics simulation
KW  -bone tissue
KW  -Bone remodeling
KW  -integrative modeling
AB  - In the present study an object oriented integrative modeling methodology is proposed for the construction of synthetic, computational models of bone-bone environment system that allow its simulation under in vivo conditions. The analytical mathematical approach to model and study ordinary materials will be outlined, indicating its limitations when dealing with biomaterials in physiological environments. The proposed object oriented integrative modeling will be explained emphasizing its advantages and possibilities. Finally, the architecture of the &#147;in vivo&#148; modeling and simulation software framework is shown, described and explained indicating further work based on this framework.
ER  - 