TY  - JOUR
T1  - Effect of Serum Trace Minerals on the Metabolism of Thyroid Hormones in Male and Female
Lambs
AU - Ramin, A.G. AU - Ramin, S. AU - Kabodi, S. AU - Asri-Rezaei, S. AU - Jalilzadeh, G.H. 
JO  - Agricultural Journal
VL  - 17
IS  - 1
SP  - 1
EP  - 8
PY  - 2022
DA  - 2001/08/19
SN  - 1816-9155
DO  - aj.2022.1.8
UR  - https://makhillpublications.co/view-article.php?doi=aj.2022.1.8
KW  - T3
KW  -T4
KW  -TSH
KW  -microelements
KW  -lamb
AB  - Based on genetic factors, trace minerals are
essential for thyroid function and hormone metabolism.
For this purpose, serum levels of thyroid hormones and
some blood micronutrient concentrations in lambs were
determined, compared and their relationships were
investigated. The 176 lambs including 70 males under 2
months old and 106 females aged 2-8 months were
selected from Ghezel and Makui breeds. The 5 mL
Jugular blood was prepared and the sera were evaluated
for the concentrations of T3, T4, TSH, copper (Cu), iron
and zinc. Thyroid hormones were determined by ELISA
and trace minerals by autoanalyzer method. Mean T3 and
TSH in males were higher than in females and T4 in
females were higher than in males but only TSH was
significant (p<0.01). The mean serum concentrations of
Cu, iron (Fe) and zinc (Zn) in males were lower than in
females in that only Cu and Zn were significant (p<0.01)
and iron was not different. TSH in males was 36.3%
higher than in females, Cu and Zn in females were 12.6%
and 7.3% higher than in males, respectively. The T3:T4
ratio was higher in males than in females and for overall
samples the T3:T4 ratio was low. There were significant
negative relationships between T3/TSH (r = -0.36) and
T4/Cu (r = -0.24) in males but not in females. There was
a significant negative relationship between TSH/T3
(r = -0.16) for all lambs. Significant positive relationships
were found between Cu/Zn (r = 0.38) and Fe/Zn (r = 0.44)
in males, females and for overall (p<0.01).
ER  -