TY  - JOUR
T1  - A Preliminary Study of Hudu’s Score as a Prognostic Scoring System of
Predicting the Risk of Liver Cirrhosis in Patients with
Chronic Hepatitis B Infection
AU - Hudu, Shuaibu Abdullahi AU - Niazlin, Mohd Taib AU - Nordin, Syafinaz Amin AU - Tan, Soek Siam AU - Sekawi, Zamberi 
JO  - International Journal of Tropical Medicine
VL  - 14
IS  - 2
SP  - 17
EP  - 20
PY  - 2019
DA  - 2001/08/19
SN  - 1816-3319
DO  - ijtmed.2019.17.20
UR  - https://makhillpublications.co/view-article.php?doi=ijtmed.2019.17.20
KW  - chronic Hepatitis B patients
KW  -prognostic factors
KW  -liver cirrhosis
KW  -Hepatitis B scoring system
KW  -viral serology
KW  -Hepatitis B
AB  - Hepatitis B infection long term prognosis is good in the absence of liver cirrhosis. However, the
risk of liver cirrhosis developing in chronic Hepatitis B surface antigen positive varies from 1-5/100
patients per year. This study aimed at developing a novel prognostic scoring system to predict liver cirrhosis
in chronic Hepatitis B patients. A total of 82 chronic Hepatitis B patients were recruited retrospectively in a
cohort study and their liver Biochemistry, Hepatitis B viral DNA level, viral serology, quantitative Hepatitis
B e Antigen (qHBeAg) and development of liver cirrhosis were assessed. The data were included in a
multivariate logistic regression analysis based on which this prognostic scoring system was established. A
simple scoring system composed of virological and biochemical laboratory parameter was developed to predict
liver cirrhosis in chronic Hepatitis B patients. This prognostic score is accurate and reproducible. The
prognostic score ranges between 5 and 15. Patients prognostic score of 5 indicates low risk, 10 high risk and
15 very high risk of developing cirrhosis. In conclusion, this study has showed a promising scoring system that
can be use in predicting the risk of developing liver cirrhosis in chronic Hepatitis B patients.
ER  -