TY  - JOUR
T1  - In vitro</I> Comparative Antioxidative Potentials of Mango and Pawpaw Leaf Extracts
AU - Olabinri, P.F. AU - Ehigie, L.O. AU - Bello, O.O. AU - Olaleye, M.T. AU - Olabinri, B.M. 
JO  - International Journal of Tropical Medicine
VL  - 5
IS  - 2
SP  - 40
EP  - 45
PY  - 2010
DA  - 2001/08/19
SN  - 1816-3319
DO  - ijtmed.2010.40.45
UR  - https://makhillpublications.co/view-article.php?doi=ijtmed.2010.40.45
KW  - biomarker
KW  -active principle
KW  -reactive oxygen
KW  -scavenger
KW  -Bioactive compound
KW  -phytoconstituents
AB  - The influence of concentration on hydroxyl radical scavenging and antioxidant activities of polyphenol extracts of Mango and Pawpaw leaves were assessed <I>in vitro</I>. The polyphenol extract from Mango leaves failed to scavenge hydroxyl radical at all the concentrations (50-250 &#956;g mL<SUP>-1</SUP>) while Pawpaw leaves failed to scavenge hydroxyl radical at three different concentrations out of five concentrations investigated (50-250 &#956;g mL<SUP>-1</SUP>). The polyphenol extract from Pawpaw leaves was a poor scavenger of hydroxyl radical <I>in vitro</I> (4.2% maximum scavenging activity). The polyphenol extracts of Mango and Pawpaw leaves exhibited weak antioxidant activities <I>in vitro</I> at all the concentrations investigated. Mango leaves had the highest total phenolic concentration (128 mg mL<SUP>-1</SUP>) at the maximum extraction time (50 min). At 50 min extraction time both the aqueous extracts of the two plants demonstrated maximum antioxidants activity (86.95% for aqueous extract of Mangifera indica and 89.70% for Pawpaw aqueous extract). A non-significant moderate positive correlation was observed between total phenolic concentration and antioxidant activity of aqueous extract of Mangifera indica and that of Pawpaw leaves (r = 0.592; p = 0.05 for Mangifera indica; r = 0.469; p = 0.05 at 20 min extraction time).
ER  -