TY  - JOUR
T1  - <I>Cynodon dactylon</I> Rhizome Extract Decreases the Cardiovascular Biomarkers
(Cardiac Troponin I and Homocysteine) and Adenosine Deaminase
Activity in Alloxan-Induced Diabetes Mellitus in Cats
AU - Azimzadeh, Kaveh AU - Hayatrouhi, Ali AU - Amanzadeh, Kurosh 
JO  - Research Journal of Pharmacology
VL  - 10
IS  - 2-6
SP  - 6
EP  - 12
PY  - 2016
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2016.6.12
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2016.6.12
KW  - diabetes mellitus
KW  -cardiovascular biomarkers
KW  -Cynodon dactylon
KW  -cat
KW  -ADA
AB  - The aim of this study was to evaluate the plasma changes of cardiac Troponin I level (cTnI),
Homocysteine (Hcy) and the activity of Adenosine Deaminase (ADA) in the alloxan-induced diabetes mellitus
and following administration of pure <i>Cynodon dactylon</i> extract in the diabetic cats. Diabetes Mellitus (DM) is
known as a metabolic disease which is followed by different blood and tissue complications. In this study, the
cTnI, Hcy and ADA activity was measured in diabetic group after 3 months administration of <i>Cynodon
dactylon</i> extract in three 150, 300 and 450 mg kg<sup>&#150;1</sup> doses. The significant increase (p&lt;0.01) in cTnl, Hcy and
ADA parameters in diabetic (positive control) group was determined in comparison to the control group
(negative control) and a significant decrease of those ones (p&lt;0.01) in the 450 mg kg<sup>&#150;1</sup> dose of <i>Cynodon
dactylon</i> in comparison to the diabetic and control group. In conclusion, firstly heart damage occurs in diabetic
cats which needs more attention to this issue in DM complications management and secondly the <i>Cynodon
dactylon</i> extract extremely influences the reduction of above-mentioned parameters and usage of dried powder
of <i>Cynodon dactylon</i> in the food of the diabetic cats may play important role in the cardiovascular health and
increasing the glucose consumption by cells.
ER  -