TY  - JOUR
T1  - Evaluation of Antibacterial and Structural Elucidation of Biological Compounds from <I>Gymnema kollimalayanum</I> A. Ramachandran and M.B. Viswan: A New Record Plant
AU - Yuvarajan, R. AU - Ramachandran, A. AU - Natarajan, D. 
JO  - Research Journal of Pharmacology
VL  - 5
IS  - 1
SP  - 4
EP  - 8
PY  - 2011
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2011.4.8
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2011.4.8
KW  - Gymnema kollimalayanum
KW  -GC-MS
KW  -India
KW  -antibacterial tests
KW  -human pathogenic bacteria
AB  - The prime aim of present investigation was focused on the <I>in vitro</I> antibacterial and GC-MS analysis of <I>Gymnema kollimalayanum</I>, a new record plant from India. The aqueous and 5 different organic solvents (chloroform, acetone, methanol, ethanol and dichloromethane) extracts were tested against both gram negative and gram positive bacterial strains by agar well diffusion assay (<I>Staphylococcus aureus</I>, <I>Streptococcus pneumoniae</I>, <I>Bacillus substilis</I>, <I>Escherichia coli</I>, <I>Pseudomonas aeruginosa</I>, <I>Proteus vulgaris</I>, <I>Klebsilla pneumonia</I> and <I>Salmonella typhi</I>). The results highlights that the chloroform, acetone and aqueous extracts exhibited significant antibacterial activity than other solvents. The results of GC-MS analysis shows ten biologically active compounds were isolated. Out of these, two compounds are reflecting the highest peak values.
ER  -