TY  - JOUR
T1  - Optimization of Antimicrobial Metabolites Production by <I>Streptomyces albidoflavus</I>
AU - , K.J.P. Narayana AU - , M. Vijayalakshmi 
JO  - Research Journal of Pharmacology
VL  - 2
IS  - 1
SP  - 4
EP  - 7
PY  - 2008
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2008.4.7
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2008.4.7
KW  - Streptomyces albidoflavus
KW  -antimicrobial metabolites
KW  -optimization
AB  - Attempts were made to optimize the culture conditions for the production of antimicrobial  metabolites by <I>Streptomyces albidoflavus. </I>Antimicrobial metabolites production was started after 72 h of incubation of culture broth and reached its maximum levels after 120 h and thereafter gradually declined. The culture medium adjusted to pH 7.0 supported the production of antimicrobial metabolites as compared to other pH levels and optimum temperature for antimicrobial  metabolite production was found to be 35°C. Basal medium amended with maltose and soybean meal as carbon and nitrogen sources, respectively was proved to be the best for the production of bioactive  metabolites. Among different minerals tested, only K<SUB>2</SUB>HPO<SUB>4</SUB> showed positive influence on antibiotic production by the strain.
ER  -