TY  - JOUR
T1  - <I>Ex vivo</I> Anti-Oxidation Activity of Polysaccharides from Red Alga <I>Porphyra yezoensis
</I>
AU - , Feng Liu AU - , Juan Liu AU - , Jiawen Gu AU - , Luxi Zhang AU - , Weirong Shen AU - , Tingting Guo AU - , Chengchu Liu AU - , Peimin He 
JO  - Research Journal of Pharmacology
VL  - 1
IS  - 3
SP  - 61
EP  - 66
PY  - 2007
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2007.61.66
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2007.61.66
KW  - Porphyra yezoensis
KW  -polysaccharide
KW  -anti-oxidation
KW  -free radical
KW  -DPPH
KW  -MDA
AB  - In this study, the <I>ex vivo</I> anti-oxidation activity of polysaccharide extracted from the red seaweed <I>Porphyra yezoensis</I> was studied. The scavenging efficiencies for free radical O<SUP>2</SUP> , •OH and •DPPH, the inhibitory effects on mice erythrocytes hemolysis induced by H<SUB>2</SUB>O<SUB>2</SUB> as well as on the lipid peroxidation in mice liver homogenate, were systematically measured and analyzed. Results suggested that Porphyra polysaccharide, in the experimental concentration range, possessed anti-oxidation activity. The scavenging efficiency for O<SUP>2</SUP>  was found to be remarkably high and the maximum scavenging rate was 82.77%. The Scavenging efficiency for •OH was even higher than O<SUP>2</SUP>  with a maximum removing rate of 85.63% and the scavenging for •DPPH was 13.97%. The inhibitory effects on mice erythrocytes hemolysis and MDA formation in mice liver were significant and the maximum inhibition rates were 82.90 and 58.48%, respectively. The combined data indicated that the polysaccharide extracted from Porphyra had strong anti-oxidation activity.
ER  -