TY  - JOUR
T1  - Evaluation of <I>in vivo</I> Antiplasmodial Activity of Ethanolic Leaf Extract of <I>Lasianthera Africana</I>
AU - , E. Okokon Jude AU - , S. Antia Bassey AU - , A. Essiet Grace AU - , Lucky L. Nwidu 
JO  - Research Journal of Pharmacology
VL  - 1
IS  - 2
SP  - 30
EP  - 33
PY  - 2007
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2007.30.33
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2007.30.33
KW  - Antiplasmodial activity
KW  -ethanol leaf extract
KW  -Lasianthera africana
AB  - The <I>in vivo</I> antiplasmodial activity of the ethanol leaf extract of <I>Lasianthera africana</I> grown particularly for the leaf in Niger Delta region of Nigeria was evaluated in <I>Plasmodium berghei</I> infected mice. <I>Lasianthera africana </I>(1000-3000 mg.kg.day<SUP>1</SUP>) exhibited significant (p< 0.05) blood schizonticidal activity both in 4- day early infection test and in established infection with a considerable mean survival time though not comparable to that of the standard drug,chloroquine, 5 mg. kg. day<SUP>1</SUP>. The leaf extract possesses significant (p< 0.05) antiplasmodial activity, which can be exploited in malarial chemotherapy.
ER  -