TY  - JOUR
T1  - Understanding the Association between Coronary Artery Disease and
Hyperandrogenism in Women
AU - Kazerani, Hashem AU - Hedari Moghadam, Reza AU - Rai, Alireza AU - hajimoradi, Behzad AU - Valizadeh, Laila AU - Asgari, Nader AU - Golshani, Sanam AU - Nanvaie, Rahim 
JO  - Research Journal of Medical Sciences
VL  - 10
IS  - 6
SP  - 694
EP  - 700
PY  - 2016
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2016.694.700
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2016.694.700
KW  - Hyperandrogenism
KW  -coronary artery disease
KW  -women
KW  -angiography
KW  -hirsutism
AB  - Hyperandrogenism which is characterized by excessive production of androgen by ovaries or adrenal
glands, is regarded as one of the probable risk factors for cardiovascular diseases. This study was conducted
to determine the association between coronary artery disease and hyperandrogenism in women. In this
cross-sectional study, the research population was women under 60 who were admitted to Imam Ali Hospital
of Kermanshah for angiography. The sample size included 116 people who were selected through available
sampling. Coronary artery disease risk factors were evaluated using interview technique and taking patient’
medical history. Blood sample was taken and tested to measure testosterone and blood glucose and lipids
variables. Then, all patients were undergone coronary angiography. Data were analyzed using SPSS-16 software
and Chi-square, t-test and regression statistical tests.Out of 116 patients under study, 58 people had abnormal
angiography and 58 patients normal one. Among the studied heart risk factors, history of diabetes, family
history of CAD and the history of previous MI in abnormal angiography group were significantly greater than
normal group (p<0.05). Considering the hyperandrogenism symptoms, hirsutism and androgenetic alopecia in
abnormal angiography group were significantly greater than normal group (p<0.05). In addition, the regression
test results also indicated the presence of a significant relationship between BMI, history of previous MI and
the presence of hirsutism symptom with the incidence of positive findings in angiography (p<0.05). The results
of this study showed that hyperandrogenism symptoms could be considered as one of the risk factors
associated with cardiovascular diseases.
ER  -