TY  - JOUR
T1  - Assessment of Epicardial Adipose Tissue Thickness in
Patient with Coronary Artery Disease
AU - Noori Al-Dujaili, Mohammed AU - Abdulhussein Al-dabbagh, Laith AU - Nassar Karkosh, Mohammad 
JO  - Research Journal of Medical Sciences
VL  - 10
IS  - 6
SP  - 557
EP  - 564
PY  - 2016
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2016.557.564
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2016.557.564
KW  - Adipose tissue
KW  -younger patients
KW  -diabetes
KW  -hypertension
KW  -history
AB  - One of the most killer and common silent disease worldwide is Coronary Artery Disease (CAD),
contributing high morbidity and mortality. The approximate of Epicardial Adipose Tissue (EAT) to the coronary
arteries plays an important role within the pathogenesis of CAD previous studies proved that coronary artery
disease had been recommended to be directly related to the Epicardial adipose tissue thickness. The purpose
of this study is to assess the accuracy of epicardial adipose tissues thickness in predicting coronary artery
stenosis. A cross-sectional study carried out at Al-Sader teaching medical city during the period from the first
of January to the 15th of October 2014 included 80 with coronary artery diseases underwent cardiac
catheterization regardless their age or gender. Patients with valvular hear diseases or poor echocardiographic
window were excluded. ECG, the Echocardiographic examination were performed in all patients. Three cut-off
points of thickness were used, according to the measurement point; on RV Apex = 8 mm, RV free wall
those = 10 mm and right ventricle outlet tract = 13 mm which are considered abnormal accumulation of EAT. The
data were analyzed using SPSS version 21 and appropriate statistical tests were applied. The mean of the
patients age was 52.1±9.8 (range: 25-77) years, more than two thirds (70%) of the patients were males. Smokers
represented (25%), History of hypertension (17.5%), diabetes mellitus(10%). The mean EAT thickness at RV
apex was 3.62±0.46 mm at RV free wall was 3.79±0.42 and at the RV outlet tract it was 3.9±0.45 mm, the mean EAT
thickness was higher in younger patients and decreased with the advancing age, male gender, smoking, history
of hypertension and history of diabetes are associated with larger mean EAT thickness. Because of this EAT
thickness is a great predictor of CAD with sufficient sensitivity, specificity and accuracy. Using the
echocardiographic assessment of Epicardial adipose tissue thickness can be a great assistance for clinicians
to detect the people at risk.
ER  -