TY  - JOUR
T1  - Association of Brachial Artery Flow Mediated Dilation with
Cardiovascular Risk Factors in Prehypertensive Patients
AU - Aldabbagh, Laith A. 
JO  - Research Journal of Medical Sciences
VL  - 10
IS  - 6
SP  - 551
EP  - 556
PY  - 2016
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2016.551.556
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2016.551.556
KW  - Endothelial dysfunction
KW  -obesity
KW  -hypertension
KW  -CV disease
KW  -brachial artery
AB  - Endothelial dysfunction is considered as an essential role within the pathogenesis of systemic
hypertension. Several factors involved in evolution of endothelial dysfunction including traditional
cardiovascular risk factor had been claimed. Modulation of these factors specially the reversible factors may
give us important ways for prevention of hypertension and its comorbidities in patients at risk of developing
hypertension. The purpose of this study is to determine the association among brachial artery flow mediated
dilation with the Cardiovascular risk factors in prehypertensive patients. In this study, 112 pre-hypertensive
patients were analyzed. For each patients a full medical history including the age, gender, BMI, smoking history,
physical inactivity and family history of premature CVD, followed by comprehensive physical examination was
done after which a blood sample was withdrawn for estimation of FBS, total and LDL, serum cholesterol, serum
HDL and TG After that each patient had been evaluated for brachial artery flow that mediated dilation. The
results show that impaired BAFMD is significantly associated with FBS, TC, LDL, Cholesterol while there was
no significant association with the age, TG, nor with HDL. Impaired BAFMD is also significantly associated
with gender, obesity, physical inactivity, family history of premature CV disease and smoking status. Therefore,
abnormalitis of BAFMD as index of endothelial dysfunction is significantly associated with multiple traditional
cardiovascular risk factors even in prehypertensive stage of hypertension.
ER  -