TY  - JOUR
T1  - Cardioprotective Effects of HMG-Co-A Reductase Inhibitors: Role of the Mechanisms of Preconditioning
AU - Denysiuk, Tatyana A. AU - Sernov, Lev N. AU - Lutsenko, Vladimir D. AU - Shiryaev, Oleg U. AU - Shaposhnikov, Andrey A. AU - Pokrovsky, Mikhail V. AU - Pokrovskaya, Tatyana G. AU - Korokin, Mikhail V. AU - Gudyrev, Oleg S. 
JO  - Research Journal of Medical Sciences
VL  - 9
IS  - 4
SP  - 245
EP  - 248
PY  - 2015
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2015.245.248
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2015.245.248
KW  - Endothelial dysfunction
KW  -preconditioning
KW  -statins
KW  -simvastatin
KW  -atorvastatin
KW  -rosuvastatin
KW  -endotoxin
AB  - Statins exhibit dose-dependent cardioprotective effect in the simulation of coronary occlusion infarction in rats. In the implementation of cardioprotective effects mechanisms of pharmacological preconditioning have an essential value as evidenced by removal of the effects during blockade of K+-ATP channels with glibenclamide and blockade of iNOS with aminoguanidine.
ER  -