TY  - JOUR
T1  - Macrolide-Lincosamide-Streptogramin-B (MLS<SUB> B</SUB>) Resistance Phenotypes in <I>Staphylococcus</I> Isolates from Non-Healthcare Community Surfaces
AU - A. Alzohairy, Mohammad 
JO  - Research Journal of Medical Sciences
VL  - 9
IS  - 1
SP  - 13
EP  - 17
PY  - 2015
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2015.13.17
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2015.13.17
KW  - community
KW  -MLS B
KW  -MRSA
KW  -currency
AB  - The present study was performed to investigate the phenotypic resistance of all isolated species of <I>Staphylococcus</I> to macrolide-lincosamide streptogramin-B through double disc test. One hundred eighty one strains of staphylococci, consisting 59 <I>Staphylococcus</I> aureus and 122 Coagulase-Negative Staphylococci (CNS) were collected between March and April 2013 from environmental sources such as gymnasia, shopping malls and ATM key in the Qasssim region and study was conducted at College of Applied Medical Sciences, Qassim University, Saudi Arabia. All isolates were subjected to in vitro anti-microbial susceptibility testing by using Kirby Bauer Method as per Clinical and Laboratory Standards Institute guidelines. The prevalence rate of total MLS resistance phenotype was observed in 29.8% of Methicillin-Resistant (MR) and Methicillin-Sensitive (MS) <I>Staphylococcus</I> species. The constitutive (cMLS<SUB>B</SUB> ), inducible (iMLS<SUB>B</SUB> ) and MS phenotypes prevalence was in 16.9, 16.9 and 22%, respectively among <I>Staphylococcus</I> aureus. While prevalence of constitutive (cMLS<SUB>B</SUB> ), inducible (iMLS<SUB>B</SUB> ) and MS phenotypes in coagulase negative <I>Staphylococcus</I> was 2.4, 3.2 and 16.3%, respectively. The high prevalence of cMLS<SUB>B</SUB> and inducible Clindamycin iMLS<SUB>B</SUB> resistance phenotypes in Methicillin resistance staphylococci as compared to Methicillin sensitive isolates was noticed in Qassim Province of Saudi Arabia. Therefore, we recommend that routine screening of staphylococci isolates by double-disc test is critical and necessary before the treatment so that therapeutic failure may be avoided.
ER  -