TY  - JOUR
T1  - Management and Patient Selection for BRCA Genetic Testing to Identify Women at Increased Risk for Breast and Ovarian Cancers: A Review
AU - Kumtepe, Yakup AU - Cetinkaya, Kadir 
JO  - Research Journal of Medical Sciences
VL  - 6
IS  - 2
SP  - 83
EP  - 86
PY  - 2012
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2012.83.86
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2012.83.86
KW  - Brest cancer
KW  -BRCA gene mutation
KW  -surveillance
KW  -risk
KW  -women
KW  -Turkey
AB  - Cancer caused by a mutated gene is a hereditary cancer rather than a sporadic cancer. Women who have inherited mutations in the <I>BRCA1</I> or <I>BRCA2</I> genes have substantially elevated risks of breast and ovarian cancer. Further genetic risk assessment is recommended for women who have &gt;20-25% chance of having an inherited predisposition to breast or ovarian cancer. Women with harmful mutations in either BRCA1 or BRCA2 have risk of breast cancer that is about 5 times the normal risk and a risk of ovarian cancer that is about 10-30 times normal. Mutation carriers have various options including extensive and regular surveillance, chemoprevention and risk-reducing surgery.
ER  -