TY  - JOUR
T1  - Tumor Suppressor Genes
AU - Gamudi, Donia AU - Blundell, Renald 
JO  - Research Journal of Medical Sciences
VL  - 4
IS  - 4
SP  - 280
EP  - 284
PY  - 2010
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2010.280.284
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2010.280.284
KW  - Tumour suppressor genes
KW  -neoplasia
KW  -cell cycle
KW  -proteins
KW  -DNA mutations
KW  -neoplastic growth
AB  - Tumour suppressor genes are a class of genes that have a crucial role in the genesis of neoplasia. These genes when transcribed and translated, result in the production of proteins that regulate the cell cycle, repair any DNA mutations and control apoptosis. When tumour suppressor genes are mutated, cells lose control and this leads to neoplastic growth. A good analogy is comparing a tumour suppressor gene with the brake pedal of a car. The tumour suppressor gene prevents the cell from dividing too quickly just as a brake keeps the car from going too fast.
ER  -