TY  - JOUR
T1  - Effects of Hepatitis B Infection on Haemtological Parameters in Pregnancy in Port Harcourt, Nigeria
AU - Evelyn, M. Eze AU - Buseri, F.I. AU - Wachukwu, C.K. AU - Nnatuanya, I.N. 
JO  - Research Journal of Medical Sciences
VL  - 3
IS  - 6
SP  - 194
EP  - 197
PY  - 2009
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2009.194.197
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2009.194.197
KW  - Hepatitis B
KW  -pregnancy
KW  -haematological parameters
KW  -infection
KW  -Nigeria
AB  - The effect of hepatitis B infection on the haematological parameters of 3,465 apparently healthy pregnant women attending antenatal clinic was studied over a period of 3 years in Port Harcourt, Nigeria. Fifty-seven were HBsAg positive (test) while the remaining 3,408 were HBsAg negative (control) representing a prevalence rate of 1.6%. The mean&plusmn;SD obtained for Packed Cell Volume (PCV), Haemoglobin concentration (Hb conc.), platelets, total White Blood Cell count (WBC), neutrophils, lymphocytes, eosinophils, basophils and monocytes for hepatitis B positive pregnant women (test) were 22.77&plusmn;2.86%, 7.26&plusmn;0.56 g dL<SUP>-1</SUP>, 144.23&plusmn;3.60 x10<SUP>9</SUP> L<SUP>-1</SUP>, 8.08&plusmn;0.89x10<SUP>9</SUP> L<SUP>-1</SUP>, 78.88&plusmn;2.11%, 16.68&plusmn;1.87%, 1.49&plusmn;0.71%, 0.04&plusmn;0.19% and 2.91&plusmn;1.27% in the same order. The corresponding values for hepatitis B negative pregnant women (control) were 31.96&plusmn;2.78%, 10.36&plusmn;0.76 g L<SUP>-1</SUP>, 159.84&plusmn;20.70x10<SUP>9</SUP> L<SUP>-1</SUP>, 6.73&plusmn;1.47x10<SUP>9</SUP> L<SUP>-1</SUP>, 69.12&plusmn;3.33%, 24.02&plusmn;4.01%, 2.96&plusmn;1.50%, 0.04&plusmn;0.20% and 3.84&plusmn;1.60%. The differences between the PCV, Hb conc, platelets, TWBC, lymphocyte, eosinophil and monocyte counts of test were statistically significant from that of the control (p&lt;0.05). There were no significant differences in the neutrophil and basophil counts of the test and control (p&gt;0.05). There was no significant correlation (R&lt;0.50, p&gt;0.01) between the haematological parameters and maternal age, trimester and gravidity in the control subjects. There was however, a strong positive correlation between gravidity and PCV (R = 0.54, p&lt;0.0.01) and haemoglobin concentration (R = 0.61, p&lt;0.01) in the test.
ER  -