TY  - JOUR
T1  - Determinants of COVID‐19 Vaccine Acceptance and Disease Outcomes Among Home Isolated Patients: A Descriptive Study from South India
AU - Jeeragyal, Devika AU - Deepika, Korimerla AU - Velukuri, Kiran AU - Guddeti, Hema Sree AU - Kodali, Chandana AU - Poladi, Sanjana 
JO  - Research Journal of Medical Sciences
VL  - 19
IS  - 4
SP  - 92
EP  - 99
PY  - 2025
DA  - 2001/08/19
SN  - 1815-9346
DO  - makrjms.2025.4.92.99
UR  - https://makhillpublications.co/view-article.php?doi=makrjms.2025.4.92.99
KW  - COVID‐19
KW  - vaccine acceptance
KW  - vaccine hesitancy
KW  - home isolation
KW  - disease severity
KW  - public health
KW  - India
KW  - awareness
KW  - recovery timeline
AB  - COVID‐19 has presented unprecedented challenges to global health
systems. Vaccination remains the most effective strategy to reduce
disease transmission, severity and mortality. However, vaccine
acceptance and outcomes vary across populations. This study aimed to
assess the vaccination status, determinants of vaccine acceptance,
disease severity, recovery timelines and awareness levels among
COVID‐19 positive individuals under home isolation in Chittoor, Andhra
Pradesh. A descriptive follow‐up study was conducted between June and
December 2022 at the Government Hospital, Chittoor. Adult patients
diagnosed with COVID‐19 and advised home isolation were interviewed
using a structured questionnaire. Data on vaccination status, clinical
outcomes, awareness levels and perceived barriers to vaccination were
collected via telephone. Descriptive statistics and logistic regression were
used for analysis. Out of 504 participants, 72.8% were vaccinated and
57.5% had received two doses. Family vaccination coverage was also high
(80%). Most patients (65.7%) experienced mild illness, while only 4.2%
developed severe symptoms. Symptoms requiring medical attention were
reported by 22.6%, but only 20.6% were shifted to hospital care.
Recovery to full health was delayed in many cases, with 27% taking over
two weeks. Vaccine hesitancy was low (3.2%), primarily due to fear of
adverse effects and lack of awareness. Awareness regarding when,
where, and whom to contact for vaccination exceeded 92% and 96.8%
expressed willingness to motivate family members to get vaccinated. The
findings highlight high vaccine uptake, strong community awareness and
low vaccine hesitancy among COVID‐19 patients in home isolation.
Vaccination was associated with milder illness and fewer hospital
admissions. However, delayed recovery in a subset of patients and the
presence of minimal hesitancy underscore the need for continued health
education and post‐COVID care strategies. Strengthening public trust and
ensuring equitable vaccine access remain essential to enhance pandemic
response and preparedness.
ER  -