TY  - JOUR
T1  - Diagnostic Efficacy of Fine Needle Aspiration Cytology in Solitary Thyroid Nodules
AU - Anand, Abhishek AU - Sindhu, Surbhi AU - Prajapati, Beenu 
JO  - Research Journal of Medical Sciences
VL  - 19
IS  - 1
SP  - 689
EP  - 692
PY  - 2025
DA  - 2001/08/19
SN  - 1815-9346
DO  - makrjms.2025.1.689.692
UR  - https://makhillpublications.co/view-article.php?doi=makrjms.2025.1.689.692
KW  - Fine needle aspiration cytology
KW  - thyroid nodule
KW  - solitary thyroid nodule
KW  - cytopathology
AB  - Solitary thyroid nodules (STN) are a common clinical finding, with
approximately 5% of palpable nodules being malignant. Accurate
diagnosis is essential for guiding management. Fine Needle
Aspiration Cytology (FNAC) is widely recognized as a simple, safe,
cost‐effective, and reliable diagnostic tool. To evaluate the diagnostic
efficacy of FNAC in solitary thyroid nodules in patients presenting at a
tertiary care hospital. This prospective study was conducted in the
Department of Pathology, Lord Buddha Koshi Medical College and
Hospital, Saharsa, Bihar, from July 2022 to June 2023. A total of 105
patients aged 15‐70 years with clinically or radiologically detected
solitary thyroid nodules underwent FNAC under aseptic precautions.
Smears were stained using May‐Grünwald‐Giemsa, H and E, and
Papanicolaou stains. Adequate aspirates were obtained in 98/105
cases (93.3%). Of these, 37 (37.7%) were non‐neoplastic, 58 (59.2%)
neoplastic, and 3 (3.1%) indeterminate. The most frequent non‐neoplastic
lesions included colloid goiter (27.5%) and Hashimoto’s thyroiditis
(6.05%). Among neoplastic lesions, follicular neoplasm (39.85%) was most
common, followed by papillary carcinoma (11.25%). Female
predominance was observed (M:F ratio 1:6.5), with peak incidence
in the 3rd and 4th decades. FNAC is a highly effective first‐line
investigation for solitary thyroid nodules. It provides early diagnosis,
facilitates appropriate management, and reduces unnecessary surgery.
Its utility is further enhanced when combined with the Bethesda System
for Reporting Thyroid Cytopathology.
ER  -