TY  - JOUR
T1  - A Case of Melioidosis (Localised Infection with Sepsis Type) in a Background of Uncontrolled Type 2 Diabetes Mellitus
AU - Bhakta, Promit AU - Ahmed, Rishad AU - Panchadhyayee, Sujoy AU - Qamar, Shazda 
JO  - Research Journal of Medical Sciences
VL  - 19
IS  - 1
SP  - 686
EP  - 688
PY  - 2025
DA  - 2001/08/19
SN  - 1815-9346
DO  - makrjms.2025.1.686.688
UR  - https://makhillpublications.co/view-article.php?doi=makrjms.2025.1.686.688
KW  - Melioidosis
KW  - Burkholderia pseudomallei
KW  - Localized infection
KW  - Sepsis
KW  - Type 2 Diabetes Mellitus
KW  - Tropical infection
KW  - Case report
AB  - Melioidosis, caused by Burkholderia pseudomallei, is an emerging
infectious disease in tropical regions, often presenting with varied clinical
manifestations. Patients with uncontrolled diabetes mellitus are at
increased risk due to compromised immunity. We report a case of a
52‐year‐old male with uncontrolled type 2 diabetes mellitus who
presented with high‐grade fever, localized swelling in the right axilla, and
signs of sepsis. Laboratory investigations revealed leukocytosis, deranged
glycemic control, and positive blood cultures for B. pseudomallei. Imaging
demonstrated a localized abscess without evidence of disseminated
infection. The patient was managed with intravenous ceftazidime
followed by eradication therapy using oral co‐trimoxazole. Strict glycemic
control was instituted concurrently. The patient showed significant
clinical improvement with resolution of sepsis and localized infection. This
case highlights the importance of early recognition of melioidosis in
diabetic patients presenting with localized abscess and sepsis‐like
features. Prompt diagnosis, appropriate antimicrobial therapy, and strict
control of underlying diabetes are crucial for favorable outcomes.
ER  -