TY  - JOUR
T1  - Study of Histopathological Spectrum of Ogd Scopy Biopsies at a Teritary Care Centre
AU - Nazar, Anisha AU - Geothe, Jayasree AU - Vijayaraghavan, Lilarani 
JO  - Research Journal of Medical Sciences
VL  - 18
IS  - 11
SP  - 832
EP  - 836
PY  - 2024
DA  - 2001/08/19
SN  - 1815-9346
DO  - makrjms.2024.11.832.836
UR  - https://makhillpublications.co/view-article.php?doi=makrjms.2024.11.832.836
KW  - OGD scopy
KW  - upper gastrointestinal biopsy
KW  - histopathology
KW  - gastritis
KW  - esophagitis
KW  - duodenitis
KW  - gastrointestinal malignancy
KW  - endoscopy
AB  - Upper gastrointestinal (UGI) symptoms are commonly encountered in
clinical practice and often require endoscopic evaluation.
Histopathological examination of biopsies obtained through
oesophagogastroduodenoscopy (OGD scopy) plays a pivotal role in
diagnosing a range of gastrointestinal disorders. To analyze and evaluate
the histopathological patterns observed in UGI biopsies obtained via OGD
scopy in patients presenting with gastrointestinal symptoms. This
hospital‐based cross‐sectional descriptive study was conducted over 3
years at a tertiary care center in South India. A total of 520 biopsy
specimens from the esophagus, stomach, and duodenum were analyzed
histologically using hematoxylin and eosin (H&E) staining, with special
stains applied as necessary. Patient demographics, clinical data, and
biopsy sites were documented and statistically analyzed using SPSS
version 26. Among the 520 patients, 55.8% were male and 44.2% were
female, with the majority in the 41–60 age group. Most biopsies were
from the stomach (59.6%), followed by the duodenum (20.8%) and
esophagus (19.6%). The most common esophageal lesion was esophagitis
(35.3%), while chronic gastritis (45.2%) and non‐specific duodenitis
(46.3%) predominated in the stomach and duodenum, respectively.
Malignant lesions included gastric adenocarcinoma (14.8%), esophageal
squamous cell carcinoma (27.4%), and duodenal adenocarcinoma (7.4%).
OGD scopy biopsies reveal a wide histopathological spectrum. Chronic
gastritis, esophagitis, and duodenitis are common benign findings, while
notable malignancies highlight the importance of routine biopsy and
histological evaluation in improving diagnostic accuracy and patient
outcomes.
ER  -