TY  - JOUR
T1  - A Prospective Study on the Role of Fall Risk Stratification and Multimodal Intervention in Preventing Fragility Fractures Among Geriatric Patients with Osteoporosis
AU - Agarwal, Saurabh AU - Agarwal, Ayush 
JO  - Research Journal of Medical Sciences
VL  - 10
IS  - 6
SP  - 753
EP  - 759
PY  - 2016
DA  - 2001/08/19
SN  - 1815-9346
DO  - makrjms.2016.6.753.759
UR  - https://makhillpublications.co/view-article.php?doi=makrjms.2016.6.753.759
KW  - Fragility fracture
KW  - fall prevention
KW  - osteoporosis
KW  - FRAX score
KW  - multimodal intervention
AB  - <p style="text-align:justify">Fragility fractures among geriatric patients with osteoporosis are frequently precipitated by falls, making fall prevention a key therapeutic target. While tools for fall risk stratification exist, their integration with multimodal interventions in real‐world geriatric care remains underexplored. To evaluate the effectiveness of a fall risk stratification‐based multimodal intervention in reducing incident fragility fractures among elderly patients with osteoporosis. A prospective interventional study was conducted at Saraswati Institute of Medical Science, Unnao, in 2015. A total of 240 osteoporotic patients aged &gt;65 years were stratified into risk groups using validated fall risk tools and subsequently allocated to either a targeted multimodal intervention (n=120) or routine care (n=120). Interventions included supervised exercises, vitamin D/calcium supplementation and home safety assessments. Outcome measures included changes in fall risk scores, incidence of new fragility fractures over 12 months and time to first fracture. Statistical analyses comprised Kaplan‐Meier survival curves, ROC curve analysis and multivariate logistic regression. At 12‐month follow‐up, the intervention group demonstrated a significantly lower incidence of fragility fractures (10.8%) compared to the control group (21.7%, p=0.02). Fall risk scores improved significantly across multiple domains. ROC analysis identified FRAX with BMD (AUC 0.79) and TBS (AUC 0.73) as top predictors of fracture risk. Logistic regression trends supported the protective role of skeletal metrics, although no single predictor reached statistical significance. A stratified, multimodal fall prevention strategy effectively reduced incident fragility fractures and improved functional metrics in elderly osteoporotic patients. Incorporating bone health assessments with validated risk tools offers a promising avenue for geriatric fracture prevention.</p>

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