TY  - JOUR
T1  - Degradation of a Nonsteroidal Anti-Inflammatory Drug Using
Horseradish Peroxidase Enzyme
AU - Montanez-Hurtado, Edna AU - Pramparo, Laura 
JO  - Research Journal of Applied Sciences
VL  - 13
IS  - 7
SP  - 425
EP  - 430
PY  - 2018
DA  - 2001/08/19
SN  - 1815-932x
DO  - rjasci.2018.425.430
UR  - https://makhillpublications.co/view-article.php?doi=rjasci.2018.425.430
KW  - Diclofenac
KW  -enzymatic treatment
KW  -horseradish peroxidase
KW  -pharmaceutical compounds
KW  -removal efficiency
KW  -temperatures
AB  - Due to the persistent feature of some compounds commonly found in wastewaters, their treatment
is very difficult through conventional processes. Therefore, alternatives among which arises the enzymatic
treatment are in continuously sought. The objective of this research is to analyze the feasibility of degradation
of a widely used pharmaceutical compound, diclofenac, using the enzyme Horseradish peroxidase as a catalyst
of the reaction. Very promising results were obtained, since, there is no evidence of the use of this enzyme for
the elimination of diclofenac compound. The influence of the initial concentration of enzyme and hydrogen
peroxide in the removal efficiency is analyzed. A maximum value of removing close to 47% was reached when
hydrogen peroxide and diclofenac were used in stoichiometric quantities. The operating conditions were also
studied. It was observed that reaction can be performed in a pH range between 6-9 and temperatures
from 20-50°C.
ER  -