TY  - JOUR
T1  - A Case for the Use of Herbal Extracts in Oral Hygiene: The Efficacy of <I>Psidium guajava</I>-Based Mouthwash Formulations
AU - , Charles O. Esimone AU - , Chukwuemeka S. Nworu AU - , Ubong S. Ekong AU - , Ifeanyichukwu R. Iroha AU - , Chidimma S. Okolin 
JO  - Research Journal of Applied Sciences
VL  - 2
IS  - 11
SP  - 1143
EP  - 1147
PY  - 2007
DA  - 2001/08/19
SN  - 1815-932x
DO  - rjasci.2007.1143.1147
UR  - https://makhillpublications.co/view-article.php?doi=rjasci.2007.1143.1147
KW  - Antimicrobial
KW  -halitosis
KW  -herbal mouthwash
KW  -herbal formulations
KW  -Psidium guajava
AB  - Aqueous leaf extract of a tropical variety of <I>Psidium guajava</I> L. (Myrtaceae) was used to formulate five batches of herbal mouthwash. The antimicrobial potentials of these herbal mouthwash formulations in oral hygiene were assessed <I>in vitro</I> using a modification of the conventional methods for evaluating oral antiseptics.  Formulations  containing  only <I> Psidium  guajava</I>  leaf  extract  and   a   standard  mouthwash (Minty Brett)<SUP>&reg;</SUP> served as controls. The mouthwash formulations were screened for antimicrobial activities against cultures of <I>Staphylococcus aureus</I>, <I>Escherichia coli</I> and <I>Candida albican</I>. The extinction time of each formulation batch was determined against each test organism. The five batches containing <I>Psidium guajava</I> aqueous extract showed a high level of activity against the test organisms-<I>E. coli</I> and <I>S. aureus</I> comparable to the activity shown by the standard mouthwash, Minty Brett<SUP>&reg;</SUP>. The batch containing only aqueous extract of <I>Psidium guajava </I>had the least extinction time of 15 and 20 min against <I>E. coli</I> and <I>S. aureus</I>, respectively. The study encourages further stability and <I>In vivo</I> assessment to develop <I>P. guajava</I> leaf extract as an ingredient of commercial mouthwashes.
ER  -