TY  - JOUR
T1  - Anti-Oxidant and Anti Tyrosinase Effect of Zizyphus spina-christi Seed Extract
AU - Hassan Maina, Ibrahim AU - Abubakar Yabo, Yahaya AU - Ishaq Ja`afar, Abdullahi AU - Habibullah, Sadiq AU - Abdul Abubakar, Adamu AU - Sa`idu, Bashir AU - Idowu Onifade, Keneth AU - Jibreen Hassan, Abdurahman 
JO  - Research Journal of Biological Sciences
VL  - 15
IS  - 2
SP  - 15
EP  - 21
PY  - 2020
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2020.15.21
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2020.15.21
KW  - Zizyphus spina-christi
KW  -medicinal plant
KW  -free radicals
KW  -antityrosinase
KW  -Anti-oxidant
KW  -produce
AB  - Medicinal plant such as Ziziphus Spina-Christi
(ZSC) has been used for the treatment and prevention of
several ailments in human and animals.It is recommended
for the management of diseases in which free radical
species are produced as a result of oxidative stress.
However, there is lack of systematic study on the
antioxidant and antityrosinase capacities of ZSCF from
Nigeria. The present study quantifies the anti-oxidant and
anti tyrosinaseability of the ZSCF grown in the Gwaski,
Southern Borno state Nigeria. Antioxidant activity was
assessed by using 2, 2-Diphenyl-1-Picrylhydrazyl
(DPPH), Superoxide-Radical Scavenging Activity
(SRSA), Ferric Reducing/Antioxidant Power (FRAP
assay). Overall the ZSCF showed strong antioxidant
ability and high anti tyrosinase effect. There is variation
in the oxidation power (DPPH) with 15.5% at the
concentration of 7.8 μg mLG1-88.4% at 1000 μg mLG1
and 22.5% at 7.8 μg mLG1 as well as 63.5% at 1000 μg
mLG1 for FRAP assay. The percentage antityrosinase
activities varied from 4.1% at 7.8 μg mLG1 -70.5% at
1000 μg mLG1 for plant crude extract. The observed
antioxidantand anti tyrosinase ability of ZSCF may be due
to abundant presence of phenolic contents and high
electron donating ability to neutralize free radicals.
ER  -