TY  - JOUR
T1  - Geometric and Histopathologic Assessment of Lavender Extracts (<I>Lavandula stoechas</I>) on Healing of Experimental Skin Wounds and its Comparison with Zinc Oxide on Rats
AU - Rezaie, Ali AU - Lotfollahi, Babak AU - Mohajeri, Daryoush AU - Mousavi, Ghafour AU - Nazeri, Mehrdad AU - Zakhireh, Solmaz AU - Mohammadi, Babak 
JO  - Research Journal of Biological Sciences
VL  - 6
IS  - 11
SP  - 585
EP  - 589
PY  - 2011
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2011.585.589
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2011.585.589
KW  - Lavandula stoechas
KW  -zinc oxide
KW  -healing
KW  -skin wounds
KW  -rats
KW  -Iran
AB  - Acceleration in healing of surgical skin wounds, in order to reduction of post-operation consequences is most important. One of the most popular compounds used ever for skin care is lavender oil or <I>Lavandula stoechas</I> essential oil. The aim of this study was evaluate the healing effects of <I>Lavandula stoechas</I> extract in comparison with zinc oxide ointment on full thickness experimental open surgical skin wound healing in the rats. For this purpose, 75 female Wistar rats were randomly assigned in 5 groups of 15 animals each including: Control, treated by Eucerin as the placebo, treated by zinc oxide topical ointment and two remaining as test groups which received 10 and 20% <I>Lavandula stoechas</I> extracts. Under the general anesthesia and analgesia circumstances, a full thickness incisional open wound with 23 mm diameter was made on the skin of the back part of the rats. The healing process was studied macroscopically and microscopically at 0 (the day of surgery) 3, 7, 14, 21 and 28th days of experiment in all of the rats. The greatest degree of wound contraction was considered in <I>Lavandula stoechas</I> extract (10%) treated rats while this change was slighter in control group. In microscopic examination, the overall healing process of <I>Lavandula stoechas</I> extract (10%) treated rats was significantly better than the other experimental groups (p&lt;0.05). The results obtained showed that <I>Lavandula stoechas</I> extract (10%) has more effective healing properties on full thickness open skin wounds compared to zinc oxide topical ointment.
ER  -