TY  - JOUR
T1  - Evaluation of the Anti-Motility Related Diarrhoeal Activity of the Sage Tea <I>Salvia officinalis</I> L. in Laboratory Mice
AU - AL-Maamori, Jafar Abbas Issa 
JO  - Research Journal of Biological Sciences
VL  - 6
IS  - 1
SP  - 33
EP  - 36
PY  - 2011
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2011.33.36
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2011.33.36
KW  - sage tea S. officinalis L.
KW  -substance
KW  -castor oil
KW  -Motility-related diarrhoea
KW  -loperamide
KW  -Iraq
AB  - Sage tea <I>Salvia officinalis</I> L. extract was evaluated scientifically for its anti-motility-related diarrhoeal effect of mice in current study by using castor oil as laxative agent-induced diarrhoea model against loperamide as standard anti-motility-related diarrhoeal drug. Fifteen male mice were used and divided into three groups (5 animals group<SUP>-1</SUP>) <SUP>+ve</SUP>control, <SUP>-ve</SUP>control (loperamide treatment) and sage tea treatment groups, respectively. The results reported a reduction in purging index (137.78), significantly decreasing of the latency period (0.90&plusmn;0.10) and number of stools (1.24&plusmn;0.19) of <I> S. officinalis </I>L. sage tea treatment group as compared to <SUP>-ve</SUP>control (loperamide) (153.85), (2.00&plusmn;0.32) and (1.30&plusmn;0.20) and <SUP>+ve</SUP>control groups (254.72), (5.40&plusmn;0.81) and (2.12&plusmn;0.10), respectively. Concludes from these findings that an inhibitory action of motility-related diarrhea effect of<I> Salvia officinalis </I>L. extract is evident from the experimental model like castor oil induced diarrhea may be attributed to therapeutic properties of this plant which contains pharmacologically active substances with anti-motility related diarrheal properties.
ER  -