TY  - JOUR
T1  - Antibacterial Activity of Silver/Clay/Chitosan Bionanocomposites
AU - Abdul Hamid, Azizah AU - Ibrahim, Nor Azowa AU - Yunus, Wan Md Zin Wan AU - Darroudi, Majid AU - Shameli, Kamyar AU - Bin Ahmad, Mansor AU - Zargar, Mohsen 
JO  - Research Journal of Biological Sciences
VL  - 4
IS  - 11
SP  - 1156
EP  - 1161
PY  - 2009
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2009.1156.1161
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2009.1156.1161
KW  - montmorillonite
KW  -bionanocomposites
KW  -silver nanoparticles
KW  -Antibacterial activity
KW  -chitosan
KW  -UV-irradiation
AB  - A simple synthesis of silver/montmorillonite/chitosan (Ag/MMT/Cts) Bionanocomposites (BNCs) with controllable sizes is presented. In this research, reduction process of silver cations by UV-irradiation was performed. AgNO<SUB>3</SUB>, MMT and chitosan were used as a silver precursor, solid support and stabilizer, respectively. The properties of Ag/MMT/Cts BNCs were studied as a function of UV-irradiation time. We found that UV-irradiation disintegrated the silver nanoparticles (Ag-NPs) into smaller size until a relatively stable size and size distribution were achieved. The average size, size distribution and crystalline structure of Ag-NPs were determined by Transmission Electron Microscopy (TEM) and Powder X-Ray Diffraction (PXRD). The antibacterial activity of Ag-NPs was investigated against Gram-negative bacterium (<I>Escherichia coli </I>(<I>E. coli</I>)) and Gram-positive bacteria (<I>Staphylococcus aureus </I>(<I>S. aureus</I>) and Methicillin-Resistant <I>Staphylococcus Aureus </I>(MRSA)) by disk diffusion method using Muller-Hinton Agar (MHA) at different sizes of Ag-NPs. All of synthesized Ag/MMT/Cts BNCs were found to have high antibacterial activity. These results showed that Ag/MMT/Cts BNCs can be useful in different biological research and biomedical applications such as surgical devices and drug delivery vehicles.
ER  -