TY  - JOUR
T1  - A <I>Streptomyces sindenensis</I> Strain LS1-128 Exhibiting Broad Spectrum Antimicrobial Activity
AU - Ningthoujam, Debananda AU - Sanasam, Suchitra AU - Nimaichand, Salam 
JO  - Research Journal of Biological Sciences
VL  - 4
IS  - 10
SP  - 1085
EP  - 1091
PY  - 2009
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2009.1085.1091
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2009.1085.1091
KW  - Actinomycetes
KW  -Streptomyces sindenensis strain LS1-128
KW  -Streptomyces
KW  -lake
KW  -sediment
KW  -Loktak Lake
KW  -antimicrobial
AB  - A <I>Streptomyces</I> sp. LS1-128 (closely related to <I>S. sindenensis</I>) isolated from the sediments of Loktak Lake, the largest freshwater lake in Eastern India, shows broad spectrum antimicrobial activity with significant inhibition zones against <I>B. pumilus</I> MTCC 1607 (25 mm), <I>E. coli </I>MTCC 739 (20 mm), <I>B. sphaericus</I> MTCC 2303 (19 mm), <I>B. subtilis</I> MTCC 121 (14 mm) and <I>C. albicans</I> MTCC 227 (11 mm). LS1-128 is an aerobic, gram-positive actinomycete with off-white to brown substrate mycelium with no diffusible pigment. Spores are arranged in rectiflexible chains in the aerial mycelium. It grows well in ISP2, ISP3, ISP4, ISP5, ISP6, ISP7, <I>Streptomyces</I> Agar and Actinomycete Isolation Agar. It can degrade starch, casein and urea and has good growth on almost all carbon sources tested including L-Arabinose, D-Fructose, D-Galactose, D-Glucose, D-Mannitol, D-Rhamnose, Salicin and D-Xylose. Based on the phenotypic and genotypic characteristics, LS1-128 was found to be most closely related to <I> Streptomyces sindenensis</I> (99.927% homology). The other close relatives are <I>S. parvus</I>, <I>S. badius</I> and <I>S. globisporus</I>). LS1-128 with promising antimicrobial activities obtained from Loktak Lake sediment has been putatively designated as <I>Streptomyces sindenensis</I> strain LS1-128.
ER  -