TY  - JOUR
T1  - Efficacy Evaluation of Different Treatment Regimens with Fluticasone Propionate in Mild Persistent Asthma
AU - , Bilan Nemat AU - , M. Shoaran AU - , Asvadi Atabak 
JO  - Research Journal of Biological Sciences
VL  - 3
IS  - 12
SP  - 1373
EP  - 1375
PY  - 2008
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2008.1373.1375
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2008.1373.1375
KW  - Asthma
KW  -fluticasone propionate spray
KW  -inhaled corticosteroid
KW  -dose frequency
AB  - Asthma is a chronic airway disorder and prevalence of asthma symptoms in children is about 1-30% and is increasing in many countries. Inhaled Corticosteroids (ICS) are one of the basic therapeutic agents for asthma and their daily frequency is one of the most important factors in the patient adherence to therapy. This study was designed to compare the effect of different frequencies of Fluticasone Propionate on the treatment of mild persistent asthma. This study is a randomized clinical trial on 100 patients with mild persistent asthma at  the  age  of  2-14  years-old receiving Fluticasone Propionate 1 puff twice daily for first 3 months and then 2 puffs once daily for next 3 months are compared to 150 asthmatic patients with the same age range and severity of disease but receiving 1 puff twice daily for 6 months. There was no significant meaningful difference in therapeutic effects of Fluticasone Propionate between two studied groups but adherence to therapy was better in once-daily administered group.  Considering the lack of significant difference between two groups and increased parental adherence in first group, the lower frequencies of spray administration after a partial improvement is suggested.
ER  -