TY  - JOUR
T1  - Risk Factors of Asthma in 2-8 Years Old Children Referred to Out-Patient Clinic of  Tabriz University of Medical Sciences
AU - , Nemat Bilan AU - , Shamsi Ghaffari 
JO  - Research Journal of Biological Sciences
VL  - 3
IS  - 11
SP  - 1313
EP  - 1316
PY  - 2008
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2008.1313.1316
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2008.1313.1316
KW  - Asthma
KW  -risk factors
KW  -childhood asthma
AB  - Asthma is a chronic inflammatory disease of the small airways that results from a complex interaction between genetic and environmental factors. As mentioned in many reports from different parts of the world, the prevalence of asthma is increasing during recent years, therefore we planned this study to investigate its predisposing factors, clarifying its epidemiology in our ethnic and geographical territory. In a case-control study on 360 children in the age range from 2-8 years, we compared the presence of asthma risk factors between 2 groups including 120 asthmatic cases and 240 non-asthmatic controls. Some risk factors were significantly more prevalent in asthmatics than controls, these include: positive family history of asthma (p = 0.003, OR = 7.5), non-breastfed (p = 0.001, OR = 5.4), low birth weight (p&lt;0.001, OR = 3.54), passive smoking (p = 0.001, OR = 2.36)<I> </I>and rhinitis (p = 0.005, OR = 2.05). The most important risk factors for development of asthma were found to be positive history of asthma in first degree family, being non-breastfed and low birth weight in order of decreasing significance.
ER  -